Szafranska, Karolina; Neuman, Tanja; Baster, Zbigniew; Rajfur, Zenon; Szelest, Oskar; Holte, Christopher Florian; Kubisiak, Agata; Kus, Edyta; Wolfson, Deanna; Chlopicki, Stefan; Ahluwalia, Balpreet Singh; Lekka, Malgorzata; Szymonski, Marek; McCourt, Peter Anthony; Zapotoczny, Barlomiej (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-20)
Fenestrations in liver sinusoidal endothelial cells
(LSEC) are transcellular nanopores of 50–350 nm diameter
that facilitate bidirectional transport of solutes and macromolecules between the bloodstream and the parenchyma of
the liver. Liver diseases, ageing, and various substances such
as nicotine or ethanol can negatively influence LSECs fenestrations and lead to defenestration. Over the years, ...